NWO Take-Off Grant for organ-on-a-chip development
- Friday, 21 July 2017
PhD candidates Cinzia Silvestri, William Quiros Solano and Nikolas Gaio (start-up Biond ) and Ronald Dekker have successfully applied for a NWO Take-Off Grant (Phase 1) for organ-on-a-chip development.
"In vitro screening is a fundamental step during drug development. A crucial need of pharmaceutical companies is to assess drug safety at the early stage of the pipeline to identify and eliminate compounds that exhibit a potential for adverse drug reactions. However, at least 462 medicinal products were withdrawn from the market between 1953 and 2014, with consequences for patients, regulatory systems and pharma companies. Therefore, the traditional screening approach, based on in vitro static cell culture assays, is considered not predictive enough. This limitation has increased the interest in more realistic models: Organs-on-chips (OOCs). Organ-on-Chips are micro-fluidics devices designed to simulate in vivo human physiology by promoting cell and tissue growth in vitro.
BIOND developed an innovative microfluidic system for OOCs that provides a dynamic micro-environment suited to highly predictive cell culture models, that allows real-time recording of a comprehensive set of data of the cell culture with a user-friendly interface. In particular, this project will aim at improving the user interface focusing on three main aspects: Usability, Functionality and Versatility"
IEEE Robert Bosch MEMS Award
Lina Sarro is the 2018 recipient of the prestigious IEEE Robert Bosch Micro and Nano Electro Mechanical Systems Award. This award is to recognize and honor advances in the invention, design, and/or fabrication of micro- or nano- electromechanical systems and/or devices.
Grant for the development of smart cathethers & implants
Ronald Dekker, Vasiliki Giagka, Paul de Wit, Wouter Serdijn and Lina Sarro received a grant concerning the development of smart catheters and implants. The project is financed by ECSEL Innovation actions, Call 2017.